Image: Bohr effect

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Description: First description of the Bohr effect, upon which pH affects binding of oxygen by hemoglobin. This is also one of the first example of cooperative binding. X-axis: oxygen partial pressure in mmHg, y-axis % oxy-hemoglobin. The measurements were made with freshly obtained dog blood, except for the top curve, which represents horse blood.
Title: Bohr effect
Credit: Bohr, C., Hasselbalch, K., and Krogh, A. (1904) Ueber einen in biologischer Beziehung wichtigen Einfluss, den die Kohlensäurespannung des Blutes auf dessen Sauerstoffbindung übt. Skandinavisches Archiv Für Physiologie, 16(2): 402-412. doi:10.1111/j.1748-1716.1904.tb01382.x. A rough translation into English is available here (WebCite copy).
Author: Christian Bohr
Usage Terms: Public domain
License: Public domain
Attribution Required?: No

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Cooperative binding

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