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Andrew Wilkie

FRS FMedSci FRCP
Born
Andrew Oliver Mungo Wilkie

(1959-09-14) 14 September 1959 (age 65)
Education Arnold House School
Westminster School
Alma mater
Awards EMBO Member (2006)
Scientific career
Fields Medical genetics
Institutions University of Oxford
Notable students Anne Goriely (postdoc)

Andrew Oliver Mungo Wilkie (born 14 September 1959) FRS FMedSci FRCP is a clinical geneticist who has been the Nuffield professor of Pathology at the University of Oxford since 2003.

Education

Wilkie was educated at Arnold House School, Westminster School and Trinity College, Cambridge, where he was awarded a Bachelor of Arts degree in 1980 and a Master of Arts degree in 1984. He moved to Merton College, Oxford, where he was awarded a Bachelor of Medicine, Bachelor of Surgery degree in 1983 and subsequently a Doctor of Medicine degree in 1992.

Research

Wilkie's research investigates genetic disorders affecting the skull and limbs, especially craniosynostosis – premature fusion of the sutures of the skull. He identified the gene mutation responsible for Apert syndrome and the molecular pathways underlying this and other craniosynostosis conditions. These results have led to many clinical diagnostic tests.

Wilkie demonstrated that the Ras molecular pathway, the common factor in paternal age effect conditions, is also important in the development of nerves and tumours. Consequently, his work has implications for other diseases, including autism and cancer. His research has been funded by the Medical Research Council (MRC). His former postdoctoral students include Anne Goriely.

Awards and honours

Wilkie was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2002, the European Molecular Biology Organization (EMBO) in 2006 and a Fellow of the Royal Society (FRS) in 2013.

Personal life

Wilkie is the son of Douglas Robert Wilkie FRS.

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